Featuring: Hossein Ardehali, MD, PhD
Cardiovascular disease (CVD) is the number one cause of death globally, and nearly half of all U.S. adults are currently at risk for heart attack and stroke. Hossein Ardehali, MD, PhD, is working to understand the role of iron and metabolic processes in cardiovascular disease and develop new therapies that target iron accumulation in people with CVD and many other chronic diseases. He is also the director of the Northwestern University Medical Scientist Training Program (MSTP) and is invested in guiding more students to careers as physician-scientists.
“We’re hoping that our studies (with iron chelators and cardiovascular disease) in the preclinical phase, will guide us to translate those into clinical practice and treating patients with various chronic diseases. This kind of treatment is not just limited to coronary disease. We are hoping that if we see positive results, we will extend it to other chronic diseases, including neurological diseases and maybe other chronic diseases like cancer." — Hossein Ardehali, MD, PhD
Iron has long been at the center of Ardehali’s research. He says while we have sophisticated our systems in the use of iron, it can still be very damaging to cells because it can cause oxidative stress. A major goal of his research is to find ways to reduce iron in chronic diseases and therefore reduce the oxidative stress that iron can cause.
Topics covered in this show:
Recorded on May 11, 2022.
This podcast was originally released by Northwestern University Feinberg School of Medicine in September 2022.
Hossein Ardehali, MD, PhD
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