Featuring: Joseph Bass, MD, PhD
Each year the Society recognizes the meritorious achievements of endocrine researchers and clinicians worldwide. These Laureate Awards recognize endocrinologists for seminal research, meritorious service, leadership and mentorship, innovation, international contributions, public service, translation of science to practice, and lifetime achievement. The Endocrine Society will present the awards to the winners at ENDO 2023, the Society’s annual meeting. For information on nominating a deserving endocrinologist, and to learn more about these awards, please visit our Laureate Awards nomination page.
Joseph Bass, MD, PhD, was awarded the Roy O. Greep Award for Outstanding Research. This annual award recognizes meritorious contributions to research in endocrinology. Dr. Bass is the Charles F. Kettering Professor of Medicine at Northwestern University Feinberg School of Medicine in Chicago, Ill. He is one of the world's leaders in circadian biology and endocrinology. His creativity and insights as an endocrinologist were instrumental in his discovery that a mutation in a core circadian clock gene lead to abnormal glucose metabolism, hyperphagia and alterations in the control of feeding time in mice.
This pioneering work provided the molecular underpinning for current thinking about how shift work leads to obesity and diabetes and set the stage for studies on how meal timing affects health. Dr. Bass next innovatively asked the converse question of whether metabolism reciprocally influences the clock and established that the macronutrient content of diet directly modulates circadian behavior and rhythmic physiology. Most recently, he has elucidated the biochemical basis for NAD+-SIRT1 regulation of core clock function, opening insight into senescence of sleep/wake and metabolic rhythms during aging.
This article was originally published on the Endocrine Society's Laureate Awards nomination page on October 3, 2022.
Joseph Bass, MD, PhD, the director of the Center for Diabetes and Metabolism, chief of Endocrinology in the Department of Medicine, Charles F. Kettering Professor of Medicine, and professor of Endocrinology in the department of Medicine.
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