March 2026

OPHTHALMOLOGY

PRECISION BIOPSY TECHNIQUES FOR SMALL EYE TUMORS

Chris Bowen, MD, explains his specialized approach to effectively biopsying small intraocular tumors. Combining expertise in both ocular oncology and vitreoretinal surgery, Dr. Bowen demonstrates how adapting retina‑surgery tools, such as curved endo‑laser-style needles and high‑magnification visualization, allows for optimal sampling of delicate tumors.
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Dr. Bowen highlights:
  • How reshaping a 27‑gauge needle to mimic an endo‑laser curvature improves access and precision
  • Why angled entry is critical for getting enough diagnostic and genetic material
  • How a low‑cut‑rate vitrectomy technique (using 25- to 27-gauge cutters) can provide additional cellular yield
  • How these refined methods guide diagnosis, inform treatment decisions and improve patient care
Chris Bowen, MD, Assistant Professor of Ophthalmology at Northwestern Medicine 

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