November 2024

NEUROSCIENCES

NOVEL ULTRASOUND BREAKS BLOOD-BRAIN BARRIER TO TREAT GLIOBLASTOMA

Roger Stupp, MD, and Adam Sonabend, MD, physician-scientists at Northwestern Medicine, discuss a novel skull-implantable ultrasound device used to open the blood-brain barrier to deliver immunotherapy and chemotherapy for glioblastoma treatment. The results of the first in-human clinical trial showed a remarkable four- to six-fold increase in drug concentrations in the brain, indicating that it may revolutionize the treatment of neurological diseases.

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​Roger Stupp, MD, Chief of Neuro-oncology in the Department of Neurology and the Paul C. Bucy Professor of Neurological Surgery at Northwestern Medicine
Adam Sonabend, MD, Associate Professor of Neurological Surgery at Northwestern Medicine

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