February 2026

CARDIOVASCULAR

ENHANCE TRIAL AIMS TO STANDARDIZE SALINE CONTRAST FOR ECHOCARDIOGRAPHY BUBBLE STUDIES

Featuring: Akhil Narang, MD

Episode Summary

In this episode of Better Edge, Akhil Narang, MD, examines the phase 3 ENHANCE trial, which evaluates a novel syringe-mounted surfactant device designed to generate uniform microbubbles and reduce variability in saline contrast echocardiography. By improving right-heart opacification and the fidelity of right-to-left shunt detection, the device aims to improve diagnostic accuracy and reduce rates of non-diagnostic and repeat studies. Rooted in Northwestern Medicine Bluhm Cardiovascular Institute’s commitment to advancing translational imaging, this trial may improve both workflow efficiency and patient care.
Akhil Narang, MD, Associate Professor of Cardiology at Northwestern Medicine

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